Vosoritide is basically a daily CNP injection. It’s targeted for dwarfism but as everyone has FGFR3 receptors it can work normal children but testing would be needed.
Here’s more on CNP.<-“we developed transgenic mice with an elevated plasma concentration of CNP under the control of human serum amyloid P component promoter and exhibited that these mice showed prominent skeletal overgrowth phenotype”
CNP delays mineralization.->”The femur, skull, and spine (L2-4) measurements were longer than that of the wild-type littermates” It could potentially affect adults via spinal height even if limbs do not increase.
“CNP activates bone turnover and remodeling in vivo”
Who knows if CNP could potentially increase height in adults until it is tested….
Apparently Biomarin did test this on adults but did the adults get taller.
