Impact loading on mouse bone length

Normally, I wouldn’t draw attention to this first paper but it draws an interesting thought:  “That long term sustained loading is better for longitudinal bone growth, whereas short term intense loading is better for bone quality.”  This could be due to hydrostatic pressure being good for stimulating a cartilagenous(and thus a pro growth plate micro-environment) whereas rapid changes in fluid flow as induced by short term dynamic loading(like jumping) are better for changes in bone quality.  So I will be changing the way I will be performing LSJL, rather focusing on clamping as hard as possible I will not be clamping as hard but doing longer more sustained clamps.

Enhancement of bone quality and longitudinal growth due to free-fall motion in growing rats

“This study is to investigate the synchronous phenomena between bone quality and longitudinal length in a same subject affected by landing exercise. Physical exercise on the ground induces external loading to human body due to resistance from ground which can activate bone generation or remodeling. Especially, when the impact stimulation is applied to bone, it may improve bone quality and lengthening.
6-week-old male Wistar rats were randomly allocated to one of two conditions: free fall from 40 cm-height (I40; n = 7), and control (IC; n = 7). The impact stimulations were administered to the free fall groups, 10 times/day, and 5 days/week for 8 weeks. Structural parameters and longitudinal length of tibia were measured to quantitatively evaluate the variation in morphological characteristics and bone length with maturing.
The landing impact seems to be commonly effective on the enhancement of bone quality as well as longitudinal growth. However, the extent of enhancement may be more dominant in bone quality than longitudinal growth. On the other hand, the ratio of longitudinal growth seems to be dependent on the duration of stimuli whereas the enhancement of bone quality does not.
This study verified that free-falls exercise can be effective on the enhancement of bone qualities and promotion of vertical growth in long bones. We expect that it might be possible for the moderate impact stimulation to be proposed as an aid for prevention of bone loss and promotion of bone lengthening.”

” Bone cells accommodate to a customary mechanical loading environment, making
them less responsive to routine loading “<-thus possibly needing to cycle on and off a method of bone stimulus.  Although our goal is to target stem cells to form new growth plates and not necessarily bone cells.

“In comparison between two groups, there is no significant [differnece] at 4 week, whereas the values in I40 group exhibited slightly but significantly higher than that in IC at 8 weeks”  So there was a change in limb length but it took 8 weeks to notice a difference.  It would be interesting to see if impact loading could have an impact on animals without functioning growth plates.  If it could increase longitudinal bone growth in some other way.

the ratio of longitudinal growth seems to be dependent on the duration of stimuli whereas the enhancement of bone quality does not.”<-this is interesting maybe it’s more important to clamp for a long period of time than intensity of clamping.  This could a lot of sense if longitudinal growth is driven by fluid whereas bone mechanical parameters are driven by stimulation of osteocytes and bone cells.  Longitudinal bone growth could be driven by sustained hydrostatic pressure whereas bone quality could be driven by rapid changes in interstitial fluid flow.

Another study found “. observed significantly greater increase in bone length compared to the sedentary rats when they implemented the similar training 100 times/day in 5 days/week
on Fisher 344 rats of 3-month-old and 6-month-old for 8 weeks”

Here’s that other study:

Effects of Jump Training on Bone Hypertrophy in Young and Old Rats

“The effects of jump training on bone hypertrophy were investigated in 3, 6, 12, 20 and 27 month-old female Fischer 344 rats. The rats of all age groups were divided into jump training
(height: 40 cm, 100 times/day, 5 days/wkfor 8wks), run training (speed: 30 m/min, 1 h/day, 5 days/wk for 8wk) or sedentary group. Fat-free dry weights (FFW) of the femur and the tibia were significantly greater in the jump-trained rats than in the runtrained rats, and were significantly greater in the run-trained rats than in the sedentary rats. jump training significantly increased FNV of the femur and the tibia not only in young rats but also in
old rats, while run training did not increase FFW significantly in old rats. In young rats, both jump training and run training significantly increased the length of the femur and the tibia and the diameter of the femur. The diameter of the tibia was greater in
the jump-trained rats than in the sedentary and the run-trained rats in all age groups. The results of the present study indicate that jump training was a more effective training mode than run training for bone hypertrophy and that the effects were not limited by age. ”

According to the chart, Jump training increased length of the tibia and femur on rats younger than 12 months but actually decreased tibia and femur length on rats older than that.  So the compressive force actually denatured the tibia and femur such that it was shorter.

But in the study they do say ” In the 3 and 6 month-old rats, both jump training
and run training increased the length of the femur and the tibia and the diameter of the femur.”<-which is contrary to what the graph says.

Key LSJL studies about device design


“Knee loading is one form of joint loading modalities, which potentially provides a therapeutic regimen to stimulate bone formation and prevent degradation of joint tissues. Healing of knee injuries is sensitive to many environmental stimuli.  Since mechanical stimuli are crucial for the growth, development, and maintenance of articular cartilage and bone,
we have developed an innovative robotic knee loading device to achieve this goal. This device induces mechanical loading to stimulate articular cartilage and bone, and it potentially reduces the healing time of injuries such as bone fractures. The robotic device, described in this study, is an improved version over previous joint loading devices, in which loads are applied at specific points with non-uniform loading around the knee joint. In this paper, finite element analysis (FEA) of this robotic device has been presented that includes static structural analysis and modal frequencies of the device for two different material configurations used in the design. The study shows that the design with ABS plastic
material offers the desired margin of safety while reducing the weight and cost. ”

“The robotic device examined in this paper is designed for small levels of deformation. The intended displacement of the working device is small, a maximum of 13 mm. large
deformations are not recommendable as such deformations will critically affect the effective range of motion of device. “<-we may want larger deformations for our purposes.

” If the stresses are too high for the material selected, the device may yield, resulting in the failure of the device.”<-this can happen with a clamp without enough strength.”

” if very small magnitude of mechanical stimuli is applied fast enough then it may induce a cellular response”<-This is an interesting thought.  It’s very hard to produce a rapid mechanical stimuli physiologically.  How many bicep curls can you perform in one second?

“Osteocytes are the highly mechanosensitive cells which senses the resulting physical stimuli from mechanical forces applied on bones. They constitute of more than 90% of bone cells.
When rapid mechanical loading is applied at the end of long bone, the interstitial fluid present around the osteocytes pressurizes causing the fluid flow which creates hydrostatic
pressure throughout the bone. This hydrostatic pressure excites the osteocytes resulting in enhanced osteogenesis which decreases the healing time of the fractures, increases the bone density and will be helpful in treatment of osteoporosis and osteoarthritis”<-we want additional stimuli from the hydrostatic pressure we want hydrostatic pressure to degrade bone tissue reducing the constraining effect that bone tissue has on growth and we want the stem cells to become more fibrocartilagenous.

“To apply such a load, a device would need to have a means of producing a transverse force directly to the end of a long bone, such as at the knee. A cyclic force applied in such an area would force a slight shift of the fluid within the bone towards the opposite end of the bone in a controlled fashion”<-this is what we do with the clamp.  Produce a transverse(lateral) force directly to the end of a long bone.  It has the potential to be cyclic if you rotate and reverse the rotation of the clamp.  We may want more than a slight shift of fluid and we may not care if it’s in a controlled fashion or not.

“a maximum force of 40 N with the frequency range of 1 Hz to 5 Hz will have a promising effect on a human knee”<-Higher force may be needed for longitudinal bone growth.

” the efficacy of stimulating the osteocytes depended on the stress distribution on the knee. Based on this observation, it is projected that a position specific loading that provides a more
targeted force application on the knee is likely to further improve the efficacy of bone stimulation. It is hypothesized in that this targeted loading would contribute to the
improvement of new bone formation over a distributed loading modality. “<-maybe a smaller clamp pad and instead of clamping the knee as a whole clamping different epiphysis’ separately.  Although we don’t necessarily care about stimulating the osteocytes, we want to degrade bone tissue and stimulate stem cells.  The statement about more targeted loading still applies.

I can’t post an image of the device but look at fig 4 and 5.

” It can be seen that when maximum force of 20 N is applied on human knee, the maximum stress generated is 11.22 MPa. “<-Since around 10MPa is the chondrogenic stimulatory range this is a key pressure however you may need to degrade bone tissue as well.  This was for alluminum and steel.  Other materials were used and they were all in this same range.


“When a cyclic but controlled load with a specific frequency is applied to the bones (femur and tibia) and surrounding tissues in the knee, it affects the osseous tissue causing physical deformations.  These deformations result in pressure gradient in the intramedullary cavity of the bone. Due to this pressure difference, there is a fluid flow of molecules and nutrients.
This will result in osteoblast differentiation; a phenomenon will initiate new bone formation or osteogenesis. This can be used as a healing technique in case of bone related injuries
like fractures or diseases like osteoarthritis and osteoporosis.”<-slightly more powerful prediction in this study where they predict osteoblast differentiation and physical deformations.  They mention a specific frequency being needed.

“When the device is loaded with a human knee, the inertial load resisting the driving force is considerable.”

LSJL Update 3-19-17

Here’s the last LSJL update.

I haven’t done experimentation with the rib cage because I’ve focusing on experimentation with a new clamp to get results in the arms and legs which is primarily what people want.

Using a 1500lbs clamp means there’s far less slippage issues.  Finding the key clamping spot is paramount as if you clamp in a spot with a lot of muscle you’ll never be able to generate enough force.  I found this was the case for clamping the shoulder joint as there’s no good place to clamp without getting a lot of deltoid.  But it was sufficient for the wrists, knee, elbow, ankles, and foot.

Here’s another pic of what the clamp looks like:

So hopefully I can have some leg and arm results to start sharing.

Here’s the feet pictures:

Here’s an overhead shot to show that it’s not flattening of the arches:

Here’s a link to when I was performing LSJL solely on my right foot.  Before right was longer.  Now left is longer.

I’m working still on clamping my right hand and right thumb with the new Bessey clamp hopefully I’ll start getting stronger results and get xray results.  There’s a difference but not as strong as I would like.  I’ll keep going to see if the results can get more and the xrays will be more striking.

The rib cage may be the best candidate for LSJL experimentation

I’ve been working hard on trying to increase my hand and feet size via clamping and I’ve had some moderate measurable success and I’m working to get more.

The reason I chose the hands and feet was because I didn’t want to be limited by clamping strength in terms of getting results.  I’ve hard to order clamps that aren’t available in hardware stores and I may have to get even stronger clamps.

But one things I didn’t consider was the shape of the bones and not just the size(hands and feet bones are smaller).

The curved nature of the ribs means that LSJL is going to be more effective think of water in a curved pipe rather than a straight one.

The fluid inside the bone is going to be bouncing around all the curvatures of the rib rather than just flowing down a straight line.  And take a look at how much more cartilage there is in the ribs than there is normally that likely means that the rib bones will behave differently from long bones.

And there is already LSJL going on in the ribs, it’s called scoliosis bracing.  However, it differ from LSJL in that it’s not on the epiphysis(the weakest part of the bone) and that the load is static(although you are moving around in the brace).

Just by breathing you’re doing LSJL on the rib cage by all the expansion pressing against the ribs.

There’s also been reports of people getting larger ribs via pullovers but that is not LSJL.

Papers like this one report growth in the rib cage due to age, Quantification of age-related shape change of the human rib cage through geometric morphometrics, I couldn’t get the full study but the study established correlation between thorax(basically rib cavity size, the larger your ribs the larger the rib cavity) and age, weight, and height with weight being the largest correlation.  And weight can perform lateral loading on the epiphysis, it’s just that due to curved nature of the rib bones it needs a lot less load than other areas and people store a lot of weight in their torso.

And another region of interest is the jaw which has a lot of curves too and a lot of people are interested in the jaw due to it’s importance in sexual dimorphism and it’s perceived impact in male dominance.  Thank of Michael Cera, Zach Braff, and James Ellworth in terms of jaws.

I’m already doing LSJL on the jaw but I’m going to be working harder at it.  Then I’m going to figure out how to do a routine for the ribs.

I’ll see if I can find more evidence of rib growth over time(you can help) and post about it definitively at the next LSJL update.

LSJL Update 2-13-17 Looks like some growth

Here’s the last update.

Here’s the new feet images:

I’ve been loading only my left foot trying with clamping various parts of it.  It looks like the left foot is starting to catch up with the right although I do have confirmation bias(I want to confirm my existing opinions) but I always have confirmation bias and I see greater changes than I did before.

So I’ll keep doing what I’m doing.  See if I can get greater changes in my feet, see if I can clamp my right hand to be bigger as I have before x-rays and I can just get after xrays to get definitive solid proof, my right hand does look bigger to me but I’d rather to see if I can get more definitive growth as again I do have confirmation bias.  And of course I’m trying to clamp to increase height.

Glucosamine Sulfate Does Work In Height Increase – Breakthrough!

Due to the subject which we focus on, the types of websites and web forums that link to the website are often very unusual and un-tasteful for many people. The most common type of websites that link to our site are from sites where you have angry, single, lonely young men in their teens and early 20s who think that their lack of dating life and romance is due to their physical appearance. Maybe some of them are right and accurate in that assessment, but a lot of the guys on those places that discuss what is written on our website are often suffering from body dysmorphic disorder. Beside just complaining about how short they are, they also complain about how their facial bone structure is not perfect ie. modelesque. The word “manlet” is thrown around and jokes are made about how even guys who are 6′ 3” are not tall enough anymore, which is definitely not true and not align with reality, at least in the USA. (I am talking about the sites, Lookism, Sluthate, etc. which are not just healthy to visit or read for the normal average male)

Besides trying to grow taller, they also want to have wide jaws, high cheek bones, pronounced chins, more pronounced nose, the right forehead angle, and sometimes even talk about changing their ethnicity. These guys are just not happy with the way they look.

This website has been around for almost 5 years now, and if I also consider the fact that Tyler has brought over many blog posts he has written over the years since the early 2000s, this website has information that may be even a decade old. So in terms of the internet space, this website is the most definitive guide on the subject of height increase on the internet, at least that is written in English. Maybe there is something else like this website in another language which has the same level of authority, but I haven’t found it.

What that means is that there are quite a few guys who read the major posts and they have sourced us. The biggest, most obvious and easiest option for height increase we have stated is Glucosamine Sulphate (although I just recently showed that taking Collagen Hydrolysate was just as important).As for the exact brand of Glucosamine Sulphate to take, I personally take the Dr Joints Advanced, which was what was recommended to me by a guy who worked at a GNC close to where I live who claimed to also teach biology courses at the local university part time.

There was a famous randomized, double blind, placebo controlled study which is always sourced to validate the idea that glucosamine sulphate is effective (the results showed on average about 3 mm of increase after 8 weeks of taking 1500 mg every day), which was also the same source used in an article written by the DailyMail UK entitled “Can This Pill Make You Taller after 4 Weeks?”.

For the longest time, in the online community, from 2000 to 2013, no one was able to validate the Glucosamine Sulphate theory, since there was only anecdotal claims here and there over the years, made by people who had questionable credentials and motives. I found someone screaming about that study (McCarthy & Swindell (sp?), et. al.) on another online forum for others to look at. I read it, and reported it on this website. Since then, the compound has become the one thing that everyone has been stating which really does have high efficacy rates as if it is some fact.

Recently, multiple sites that have linked to the website has had people claiming that it does work.

I frequent reddit a lot and in a recent reddit/r/tall post, some guy who listed himself as 6′ 5” made a claim that he has been taking glucosamine sulphate to reduce the amount of height loss from spinal compression over the day (aka diurnal variation). I can’t find that exact link for that particular r/tall thread. I did clip a picture of the post but it is somewhere in my hard drive, which is a mess right now. This shows that Glucosamine has this ability to mitigate the amount of height loss.

When you consider the fact that so many americans seem to have joint problems and lower back pain, which is the result of gradual loss and degradation of articular cartilage at the end of bones and collagen/water/ECM in the intervertebral spinal discs/annulus fibrosus, taking Glucosamine everyday even starting out as early as in your 20s doesn’t seem like such a bad idea.

So many americans seem to love going to the gym, working out, and bodybuilding. They like to max out on their bench press, deadlift, and squats. I have seen too many Youtube videos of guys who have put on 40-50 extra lbs of muscle to look as wide as possible and they would do squats with 400 lbs or more on their back.

That amount of weight on one’s body is horrible for the joints. I am always reminded of the story my friend told me years ago. His mother and aunt were both huge runners when they were younger (20s and 30s) but now that they are in their 50s and 60s, they have all this joint pain from so much pounding they did on their knees for so long.

From one source –

A guy who claims to be 1.86m tall at night but wanted to be 1.90m said that we said glucosamine sulphate would give 2-3 cm is wrong! The results of the study showed an average of 3 mm, not cm. That person is a full order of magnitude off in reporting. If we said it was cm, and not mm, then I have to apologize for that error in reporting. But the results were 3 mm.
From other source –

A poster calling himself Jack_Coppit said…

“I have a little experience with these sort of supps and aminos, for some back ground I am 21 and have never had a growth spurt, just grew slowly and gradually. My Father was the same and grew until he was 25. I started taking glucosamine sulphate around 2-3 weeks ago, 2.4gs Glucosamine which was made up by 3 1000mg capsules of glucosamine sulphate. Now my height has indeed increased. Which may sound silly. However prior to taking the glucosamine, I have been taking 5 grams of L-Arginine a day for 3.5 months, and continue to do so. L-Arginine has been proven to raise your resting HGH levels and can do so even more depending on whether you exercise or if you have an empty stomach when taking it.

I started by changing up my diet, and making sure I ate foods that were perfect for raising HGH and maintaining high levels throughout the day and throughout the night. I started this thinking I was a solid 5’8, but discovered that at the end of the day I was approx 171cms 5’7. Now however, my morning height peaked at 176cm 5’9 and my evening height is 174cm. Now whether this is improved posture or with stretches I do not know, but even with days off from stretching, maybe 4 at a time, I am maintaining this height. This also could just be natural growth due to my genes allowing me to grow after 21. Who knows. All I know is that I have 100% grown during this time, I measure my eye level against things I see in real life, my 5’4 Girlfriend now has to look up to me slightly more now when I stand straight, the shelf at work I can look over a little more, and the pains I get do seem to be growing pains. TLDR; 3 grams of Glucosamine sulphate and 5 grams of L-arginine = 3cms growth in 3-4 months. 0.75cms a month currently”

He noted that the Glucosamine does thicken the cartilage at the end of bones, which does seem to be true.

From a 3rd source –

This guy who basically says he is 6′ 7” or exactly 2.024 m (which is actually 6′ 7.5” to be more exact) gained over 4 cm of height from taking Glucosamine and sticking to this specific routine.

– Hanging from a bar for 1 minutes 5x in the morning and 5x in the evening – total of 10-15 minutes a day

– Upside down hanging with gravity boots with same intervals as above
– Glucosamine – 2000 mg a day
– Posture exercise –
– Constant hydration

Morning height increase from 1.983 meters to 2.024 meters. Evening height went from 1.954 meters to 1.999 meters. Notice however that before, the loss over the day was 2.9 cms while after taking the glucosamine the loss of height over the day was only 2.5 cm!!

>This is key right here. Even if we negated everything else and assumed that 4 cm of extra height was just normal natural growth, the reduction in loss over a day shows that oral consumption of Glucosamine does have noticeable effects.

This is his breakdown of the 4 extra cm…

1 cm from glucosamine
0.5-1 cm from hanging
close to 2cm from gravity boots
0.5-1cm from posture exercises

These are the conclusions this young lad made…

Glucosamine reduced height loss and was mostly responsible for maintaining evening height.

Hanging and upside down hanging enlongated my spine which increased overall height.
The taller you are the more height you will gain from this.
A 7’5′ person might gain 6-7cm and a 5’8 cm person only 3cm.

In response to what this guy claimed, a poster noted that after being on Glucosamine for 4 months, he probably gained around 5-10 mm at most, which when you think about it is enough of a gain to be more than just variation error. The guy claimed to be 190.5 cm tall at night, and that he would loss as much as 3-4 cm over the day, which is quite sizable. Him taking Glucosamine seemed to have fixed his ruptured discs problem and helped ease his back and neck pain. He sorted of admitted that it is possible that glucosamine may indeed reduce the amount of loss in height over the day, but not increase the morning height. He would late admit that it was not a full cm but more like 0.5 cm, which is about what the original study said (0.3 cm)

The original poster did note that astronauts in zero-gravity can gain 2-3 inches of extra height (that is true), so his routine which includes hanging on a bar can probably help increase a normal increase of only 3-5 mm to something more.

Personal Thoughts and Conclusion

Glucosamine definitely works in increasing height for some people. It is not a lot. The people who read this site and actually bought it and started taking it,, and stayed with it on a routine has debated and almost argued on certain forums and websites just what is realistically possible. A lot of people say it it as little as 0.5 cm, Others like this guy who is now 6′ 7” claim that they got 4 cm, when they combined it with hanging, hydration, and stretching. 4 cm does seem extreme, and the original poster never did answer the question of just how old is he.

It does seem rather odd that a guy who is now 6′ 7” would have desires to be even taller. (I’ve heard storied before of guys who are 6′ 5″ and still wear lifts in their shoes. Guys over 6′ 0″, and often 6′ 2″ now regularly post on whatever bodybuilding forums that they don’t feel that tall and would like to be even taller if they had the chance. I don’t think there is any real way to stop this idea that bigger is always better, even for the biggest of men. “Rarely does a guy say, I am tall enough. I don’t want/wish to be any taller” No matter how big you are, there will always be someone bigger, unless you are actually the biggest in the world.) In his words, he wanted to be 1% of the population where he lives, or 6′ 9”. The way he is talking, it sounds like he is still in university in the Netherlands. He has claimed that the average height in the netherlands is 6′ 1.5” and that in the university, the guys average around 6′ 2” – 6′ 2.5”. Is this guy just height obsessed since he is already extremely tall compared to the rest of the world? I don’t know. We all have our own hang-ups. I don’t judge other people anymore since there is really no such thing as “normal”.

Side Note

There is this rather obscure video of the basketball player Blake Griffin getting his height measured at the Predraft Combine years ago (it can still be found on Youtube somewhere ). This was in the morning, and his height and weight were the first things that the doctors/trainers measured right after he got out of bed in his hotel room. So we can negate the factor that his height was decreased slightly from all the jumping and running around on the basketball court. Blake’s height is tabulated at 6′ 8.5” but in the video he said his height was 6′ 8.75”. Now, a quarter of an inch doesn’t seem like that big of a deal, but when you consider the fact that even half an inch of extra height could mean you get a couple of million more dollars a year (based on a slight bump in the draft), even a quarter of an inch can be worth discussing over. I remember really looking very closely at the video, to see whether he was 6′ 8.5” or a quarter inch taller. I personally would have given him that extra quarter inch from the video, although the guy who actually measured him was only a few inches away from the measuring tape.

My point is that if this young guy on the lookism website who claims to be 6′ 7” now can vary as much as almost a full inch over the day, it makes sense that many of these basketball players who are even taller, would have their height be even more varied.

When Magic Johnson asked Lebron in a recent video point blank just how tall he really was, Lebron said (and I quote) “about 6′ 8”. Lebron has been since his Senior Year in high school “about 6′ 8”. He is not actually 6′ 8” because there are plenty of videos where he walks through a normal US standard doorway without ever reflexively ducking,. The exact height of most US doors is EXACTLY 6′ 8”. This is a standard in door manufacturing. The doors themselves are always lifted about 0.3-0.8 cm off the ground, so the wood doesn’t scrap against the floor. So the top of all doorways is usually 6′ 8.5” – 6′ 9” tall. He has his head always shaved so you can clearly see the top of his head aligned with the top of any doorway. Lebron in shoes at 6′ 8” or slightly more has never once in any of the videos I have seen him touch the top of any normal doorway, ever. He often looks maybe half an inch off. He also never ducks. People who are tall enough to scrap the top of their head or have their hair touch the doorway would instinctively duck, from a lifetime of habit. Lebron never does that. That means that those predraft measurements you find saying he is really 6′ 7.25” is very accurate, with about a 0.25 inch of error factored in, similar to Blake’s measurement’s difference. It is very possible that Lebron is actually 6′ 8” right out of bed, and by the end of a day of jumping, squatting, weight lifting, and running he could be as low as 6′ 7” at the end of a day, which is a very reasonable amount of difference from diurnal variation. I have no doubt that he, as a professional athlete, who is probably the highest paid athlete in the world, who is said to use $1.5 Million a year just to maintain and treat his body, is probably taking some type of supplement mixture to make sure that his joints last as long as possible.

The entire point here is that especially for taller men, taking glucosamine probably has an even more pronounced effect than shorter men, since supplement consumption means that they will suffer from much lower rates of height loss over the day. Basketball players are the type of people who will have the most benefit from taking the supplement.

Next Post Will Be About Anti-Sclerotin vs Fluriprofen