Converting Bone Into Cartilage – My Primary Research Objective

Converting Bones Into Cartilage – My Primary Research Objective

I said before that the easiest way to make the bones longer is if we can bring the bones into a previous stage of development. That would mean we would need to reverse the direction of differentiation. If we remember from our older auxological analysis, all bones start off being cartilage. over time, the cartilages become vascularized, calcified, and then ossified. It could be said that ossification is the dead waster material that makes up the remnants of live tissue.

What we are doing than is trying to bring dead cell wastes in the form of dead cells back to life. We reverse the normal cell life process. That is my primary research objective.

The current ideas that I have had about how to do it is to either….

  1. Change the bone cells into cartilage cells through the right type of chemical or electrical stimuli
  2. We remove the bone cells and flush the bone ECM with cartilage cells from an exogenous source of chondrocytes.
  3. We slowly change the stem cells in the bones into cartilage while still removing the bone cells and the hard compounds (both inorganic and organic)

Of course the tissue is more than just the cell. To make cartilage, it would require also the presence of the collagen medium which the cells float and move around in. Since the bone ECM structure is extremely hard, we would need to either…

  • Remove the hard inorganic compounds
  • Convert the hard inorganic compounds into soft organic compounds,
  • Keep the organic compounds
  • Convert the organic compounds into collagen.

Of course, even by this step, which would require a long series of chemical reactions or tissue transfusions, it might be that we don’t get the right type of cartilage. That shows just how difficult it would be to figure out the overall step. How do we turn the bone tissue into cartilage tissue, and hopefully in a more non-invasive approach?