Ecommia Leaf Extract for height

This supplement is available for sale and it seems to be promising for those who have existing growth plates:

Effects of Eucommia ulmoides Extract on Longitudinal Bone Growth Rate in Adolescent Female Rats.

Full study -> eucommia

“[We] investigate the effects of E. ulmoides extract on longitudinal bone growth rate, growth plate height, and the expressions of bone morphogenetic protein 2 (BMP-2) and insulin-like growth factor 1 (IGF-1) in adolescent female rats. In two groups, we administered a twice-daily dosage of E. ulmoides extract (at 30 and 100 mg/kg, respectively) per os over 4 days, and in a control group, we administered vehicle only under the same conditions. Longitudinal bone growth rate in newly synthesized bone was observed using tetracycline labeling. Chondrocyte proliferation in the growth plate was observed using cresyl violet dye. In addition, we analyzed the expressions of BMP-2 and IGF-1 using immunohistochemistry. Eucommia ulmoides extract significantly increased longitudinal bone growth rate and growth plate height in adolescent female rats. In the immunohistochemical study, E. ulmoides markedly increased BMP-2 and IGF-1 expressions in the proliferative and hypertrophic zones. In conclusion, E. ulmoides increased longitudinal bone growth rate by promoting chondrogenesis in the growth plate and the levels of BMP-2 and IGF-1. Eucommia ulmoides could be helpful for increasing bone growth in children who have growth retardation.”

“Because components in E. ulmoides extract activate osteoblast differentiation, we hypothesized that treatment with E. ulmoides extract would increase longitudinal bone growth rate.”<-Interesting considering it’s the growth plaate that increases height.

If you look at figure 2 in the full study, the growth plate looks bigger but it doesn’t have the dramatic differences that other chemicals or methods induce in the growth plate.  Which means that the risk is that this chemical only increases growth rate and not adult height.  According to Table 1, this compound increased levels of BMP-2 and IGF-1 by up to 50% in the resting, proliferative, and hypertrophic zone.

“At the dose of 100 mg/kg, E. ulmoides caused a significant acceleration of longitudinal bone growth rate, which was 373.1 ± 24.4 µm/day (6.4%) compared with the control group, which was 350.8 ± 18.5 µm/day. At the dose of 30 mg/kg, E. ulmoides caused an acceleration of longitudinal bone growth rate of 360.5 ± 23.5 µm/day (2.8%) compared with the control group.”